The first signs of Alzheimer’s can appear in the body for more than thirty years before diagnosis, the scientists found.
The authors of the study from 1995 to 2013 followed the condition of 290 patients with increased predisposition to dementia.
By the end of this term cognitive impairment occurred in 81 of them, according to
“What is our life? Game!”“World mind games”: the premiere of “the World” it Turned out that even for 11-15 years before the symptoms anxiety symptoms these people were worse to deal with tests for memory, attention and intelligence.
But even more striking marker became elevated content of Tau-protein in cerebrospinal fluid.
Scientists have found that the amount began to grow around 34.4 years before the disease.
In addition, the experts analyzed MRI brain scans of patients. Image was processed using computer algorithms to identify anatomical changes associated with impaired cognitive functions.
The results showed that for the three-and nine years before the manifestation of abnormalities in humans slightly decreased volumes of medial temporal lobes of the brain – the area responsible for memory.
The authors of the study stressed that they discovered biomarkers may be useful for early diagnosis of Alzheimer’s disease.
Earlier, the world health organization gave recommendations for the prevention of dementia. You need to exercise, not Smoking and not addicted to alcohol, but also to control your weight, blood pressure, blood sugar and cholesterol.