According to scientists, ibuprofen may prevent the development of Alzheimer’s disease, reports the Daily Mail.
Patients with a high risk of this disease that are discovered through the analysis of saliva, can avoid dementia if they take a low dose pain reliever with the onset of middle age life, experts say.
Such conclusions were made during the study of 500 people. It is assumed that ibuprofen suppresses inflammation in the brain that leads to nerve cell death associated with Alzheimer’s disease.
Lead researcher, neurobiologist Dr. Patrick McGuire says:
“Patients can prevent the development of Alzheimer’s disease by taking the drug, which requires no prescription or doctor’s visit.
If ibuprofen will be used worldwide, Alzheimer’s disease will disappear.”
Although experts still can not be called ideal dose of ibuprofen, they believe that 1-2 tablets a day will be enough to have an effect on the brain.
Scientists plan to conduct additional tests to determine the exact dose that will be useful for the brain and safe for health.
In 2016, Dr. McGuire and his team announced that they have developed a simple saliva test that can diagnose Alzheimer’s disease.
The analysis is based on measurement of the concentration of the protein amyloid-peptide 42 (Abeta42), secreted in the saliva.
In most people the rate of production of Abeta42 is almost the same regardless of gender or age. However, if this production rate is 2-3 times higher than normal, then these people will probably develop Alzheimer’s.
This is because Abeta42 is relatively insoluble material, but it is deposited only in the brain causing neuroinflammation, which destroys neurons in the brain of people with Alzheimer’s disease.
Contrary to the widespread opinion that Abeta42 is produced only in the brain, the team of Dr. McGuire demonstrated that this peptide is found in all organs of the body and is secreted in saliva from the submandibular gland.
So it is enough one teaspoon of saliva, to determine whether a person to develop Alzheimer’s disease. This will give him the opportunity to start to take early preventive measures — for example, nonsteroidal anti-inflammatory drugs such as ibuprofen.
Dr. Macher says:
“Knowing that the manifestations of Alzheimer’s starts at 65 years of age, we recommend that people get tested 10 years earlier, at the age of 55 years, when Alzheimer’s usually begins. If the analysis shows an increased concentration of Abeta42, it is time to start to take daily ibuprofen to prevent disease.”
“Unfortunately, most clinical trials to date, dedicated to patients with cognitive deficits from mild to severe, and the therapeutic potential of at a very late stage of the disease is minimal.
Our discovery will not stop the development of disease in those already ill, but a game changer. Now we have a simple analysis, which can develop if the disease in humans, as well as a drug that can help prevent its development.
This is a real breakthrough because it indicates the direction in which Alzheimer’s can be stopped.”
We will remind, recently, scientists reported a successful case of cure of Alzheimer’s.
Here’s the good news!