New experimental vaccine against HIV has acknowledged effective
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In testing a new drug took part 393 of the volunteer.
Scientists successfully completed another phase of clinical trials of an experimental vaccine against HIV-1 most common and pathogenic type of HIV. This was reported by the journal The Lancet, reports Naked Science.
In the trial of a new drug took part 393 volunteers from southern and East Africa, Thailand and the United States aged 18 to 50 years, they have not been infected with HIV. In parallel, the tool was tested in 72 monkeys. The vaccine was supposed to protect animals from infection artificially created virus.
The authors of the study noted that when creating tools used several strains of HIV, to improve the effectiveness of the vaccine. This drug test participants received at baseline and twelve weeks.
During the test it was found that the vaccine significantly increased the activity of antibodies to HIV, the process of phagocytosis (the engulfing and destruction of foreign body material) and response of T-cells. Among the side effects of the volunteers reported dizziness, diarrhea, and back pain. In macaques, this combination also proved to be the most effective: it is defended from the virus by 67% of the animals.
In the next stage of research will involve over 2,600 women of various groups at high risk of HIV infection.
According to who, there are about 37 million people with HIV infection.
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